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Single Use Pinch Valves for Bioprocessing
Manual, Pneumatic & Electronic Pinch Valves for Biopharma and Bioprocessing Applications
Pinch valves provide precise, low-shear flow control for modern bioprocessing, enabling sterile operation without cleaning, maintenance or validation. They control flow by externally compressing single-use tubing, so no moving part ever contacts your product, which cuts contamination risk.
On ARTēVA the pinch mechanism is reusable 316L stainless steel and only the tubing is consumable, so you buy the valve once and swap nothing but the flow path between batches.
Available in manual, pneumatic and motorized configurations, ARTēVA single-use pinch valves integrate into disposable assemblies, mixing and filtration systems, perfusion skids and continuous bioprocessing platforms.
With gamma-ready materials and compatibility across a wide range of tubing sizes, they deliver repeatable performance for biopharma, cell therapy, mRNA and vaccine workflows.
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How do the ARTeVA® Single-Use Pinch Valves Work?
ARTeVA® single-use pinch valves control fluid flow by externally compressing disposable tubing, regulating or fully stopping flow without any direct contact between the valve mechanism and the process fluid. Because all product-contact surfaces are defined by the single-use tubing, flow control is achieved without introducing internal wetted components, dead legs, or moving parts into the fluid path, supporting sterile operation in closed bioprocessing systems.
The valve body incorporates internal stem guides that ensure controlled, repeatable compression of the tubing during actuation. These guides maintain consistent alignment and closing force over repeated cycles, supporting reliable flow control and reducing variability caused by misalignment or uneven tubing deformation. By mechanically guiding the actuation motion while keeping all product-contact surfaces confined to the disposable tubing, the design maintains process integrity while improving operational consistency in single-use and GMP bioprocessing environments.
ARTeVA single-use pinch valves are available in manual and actuated configurations, including pneumatic, motorized, and electronically actuated options, allowing integration into single-use assemblies, mixing and filtration skids, and automated bioprocessing platforms. The result is a flexible flow control solution that supports reliable process operation across upstream and downstream applications, from development through GMP manufacturing.