Alphinity

Single Use Valves for Bioprocessing

Single-Use Diaphragm, Manifold, and Check Valves for Biopharma Applications

The single-use pinch valve portfolio, including VannX™, Vannefold™, and SoloCheck™, is designed to provide reliable flow control for sterile, closed bioprocessing applications. Engineered specifically for use in disposable flow paths, these single-use valves integrate directly into tubing sets, manifolds, and assemblies, enabling contamination-free operation without the need for cleaning, CIP/SIP cycles, or complex validation procedures. All product-contact surfaces are defined by the single-use fluid path, while valve actuation remains external to the process fluid.

The valve range supports proportional flow control across upstream, downstream, and fill-finish operations. VannX™ single-use pinch valves are used where controlled flow regulation is required, Vannefold™ enables compact manifold branching and flexible system layout, and SoloCheck™ provides dependable backflow prevention within single-use circuits. Together, these valves support integration into modular skids, benchtop systems, and larger single-use process platforms used in GMP manufacturing.

Designed for compatibility with gamma-ready materials and common tubing formats, the single-use pinch valve platform supports consistent, repeatable performance across a wide range of bioprocessing conditions. Typical applications include media and buffer handling, perfusion circuits, filtration systems, and final fill pathways, making these valves well suited for cell therapy, mRNA, vaccine, and biologics manufacturing workflows where sterile flow control and process reliability are critical.

Single Use Diaphragm Valve
Single Use Diaphragm Valve Manifold
Trusted Process
Built with consistency and reliability at every stage.
Regulatory Ready
Designed to support compliance with medical and industrial standards.
Proven Performance
Tested across demanding applications in biotech and single-use systems.
Overmolding
Assemblies
Pumps
Valves
Overmolding
Assemblies
Pumps
Valves
Overmolding
Assemblies
Pumps
Valves